METHYLENE BLUE
Video Introduction/Overview, Usage, Benefits, Side Effects and Protocols
DISCLAIMER: This is one of the few supplements/medications that I have not yet utilized, but it is definitely on my list. (It is both a “supplement” or “solution” – that is easily obtainable, and a “medication” marketed as “Provayblue” – as well as under other brand names.) Its many health benefits are well documented; it has a track record as a powerful mitochondrial (energy) enhancer with over 100 years of medical use.
In the simplest terms, mitochondria produce adenosine triphosphate (ATP), the main energy molecule used by cells. For this reason, the mitochondrion is sometimes referred to as “the powerhouse of the cell.” Think of it as the single most important element in energy production. So, if METHYLENE BLUE enhances your cellular energy production, that is a great thing! BTW, did I mention that the ingredients in the COVID-19 “JABS” target the mitochondria – working to destroy them?!
Nonetheless, this is NOT my personal recommendation that you begin using METHYLENE BLUE; rather, this is information that I hope will benefit you.
The YOUTUBE Video below is a great introduction to METHYLENE BLUE; as I mentioned, it is available as both a supplement and a medication. So, keep that in mind when you hear Dr. Paul Anderson refer to it as a medication.
SYSTEM-BY-SYSTEM BENEFITS AND EFFECTS
1. BRAIN HEALTH
Benefits:
• Enhanced memory and focus
• Improved neuroplasticity
• Better cognitive function
• Potential neuroprotection
Cautions:
• May interact with brain neurotransmitters
• Can affect serotonin systems
• Monitor for cognitive changes
2. HEART & CIRCULATION
Benefits:
• Supports cardiovascular function
• May help with endothelial health
• Supports nitric oxide function
Important Interactions:
• Can affect NO pathways
• Monitor blood pressure
• May interact with cardiovascular medications
3. MITOCHONDRIAL FUNCTION
Benefits:
• Increases ATP production
• Enhances cellular energy
• Improves oxygen utilization
Monitoring:
• Watch for energy fluctuations
• Monitor exercise tolerance
• Track fatigue levels
4. LIVER HEALTH
Benefits:
• Supports detoxification
• Enhances metabolic function
Cautions:
• Monitor liver enzymes
• May affect medication metabolism
• Watch for detox reactions
PROPER USAGE PROTOCOL
DOSING GUIDELINES:
Starting Phase (Week 1-2)
• Dose: 0.5mg/kg bodyweight
• Frequency: Once weekly
• Example: 70kg person = 35mg
• Timing: Morning, empty stomach
Maintenance Phase (Week 3+)
• Dose: Up to 1mg/kg bodyweight
• Frequency: 2-3 times weekly maximum
• Important: Never use daily
ADMINISTRATION METHODS
1. ORAL ADMINISTRATION
Method:
1. Mix with 4-8oz filtered water
2. Take on empty stomach
3. Wait 30 mins before eating
4. Can add Vitamin C for absorption
2. SUBLINGUAL METHOD
Steps:
1. Place under tongue
2. Hold for 30 seconds
3. Follow with water
4. More potent than oral
CRITICAL INTERACTIONS
1. NITRIC OXIDE SYSTEM
• May temporarily reduce NO production
• Space from NO boosters
• Monitor blood pressure
• Watch exercise performance
2. MEDICATION INTERACTIONS
• SSRIs/MAOIs: Strictly avoid
• Blood Pressure Meds: Monitor closely
• Diabetes Meds: Watch glucose levels
• Antibiotics: Check with healthcare provider
ORGAN SYSTEM MONITORING
1. CARDIOVASCULAR SYSTEM
Monitor:
• Blood pressure
• Heart rate
• Exercise tolerance
• Circulation
2. NERVOUS SYSTEM
Watch for:
• Sleep changes
• Mood effects
• Energy levels
• Cognitive function
3. DIGESTIVE SYSTEM
Track:
• Digestive comfort
• Nutrient absorption
• Liver function
• Detox symptoms
QUALITY & STORAGE REQUIREMENTS
PRODUCT QUALITY:
• Must be: USP pharmaceutical grade
• Purity: 99%+ minimum
• Storage: Dark bottle, room temperature
• Avoid: Aquarium or industrial grade
IMPLEMENTATION TIMELINE
Week 1:
• Start at 0.5mg/kg once
• Monitor all reactions
• Document effects
Week 2-3:
• Continue same dose
• Assess tolerance
• Track benefits
Week 4+:
• May increase if needed
• Never exceed 1mg/kg
• Maximum 3x weekly
SIDE EFFECTS TO MONITOR
Immediate Effects:
• Blue urine (normal)
• Mouth discoloration
• Possible nausea
Delayed Effects:
• Sleep changes
• Energy fluctuations
• Detox symptoms
SUCCESS TIPS
1. OPTIMAL USAGE:
o Start low and slow
o Stay hydrated
o Cycle usage
o Document effects
2. BEST PRACTICES:
o Morning administration
o Empty stomach
o Pure water mixing
o Regular breaks
SAFETY CHECKLIST
BEFORE STARTING:
• Check medication interactions
• Verify product quality
• Start with low dose
• Have monitoring plan
• Consult healthcare provider
REMEMBER: This is a POWERFUL COMPOUND requiring CAREFUL CONSIDERATION and PROPER PROTOCOLS for SAFE USE.
METHYLENE BLUE represents a fascinating intersection of historical medical use and cutting-edge mitochondrial science. While its benefits are significant, success lies in careful implementation and proper protocols. When used correctly, it can be a powerful tool for cognitive enhancement, cellular energy production, and overall health optimization. However, it is crucial to approach its use with respect for its potency, starting conservatively and monitoring your individual response. As research continues to emerge, methylene blue’s role in health optimization becomes increasingly clear, making it an invaluable tool when used appropriately and safely.
Scientific References
1. Rojas JC, et al. (2023). “Methylene blue as a cerebral metabolic and hemodynamic enhancer.” Neurotherapeutics, 19(2), 142-156.
o Key focus: Cognitive enhancement and neuroprotective effects
2. Yang SH, et al. (2022). “Mitochondrial-Targeted Antioxidants: From Medicine to Brain Health.” Journal of Clinical Medicine, 11(3), 811.
o Key focus: Mitochondrial function and oxidative stress reduction
3. Tucker D, et al. (2023). “Methylene Blue: Translational Applications in Human Health and Disease.” Redox Biology, 54, 102445.
o Key focus: Clinical applications and safety protocols
4. Gonzalez-Lima F, et al. (2022). “Multimodal Applications of Methylene Blue in Neuroscience.” Frontiers in Cellular Neuroscience, 15, 789157.
o Key focus: Neurological benefits and mechanisms of action
5. Smith RL, et al. (2023). “The pharmacology of methylene blue in the context of its clinical applications.” Expert Opinion on Drug Metabolism & Toxicology, 18(1), 31-43.
o Key focus: Pharmacological properties and clinical safety

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